YBX1&YBX3 as novel targets to potentiate immune checkpoint blockade response in gliomas
These findings define a novel glioma-intrinsic immunosuppressive program and proposes targeting the CHK2-YBX1&YBX3 hub to potentiate response to ICB in glioma.
Authors
- Deanna Tiek (ORCID: https://orcid.org/0000-0002-2881-7691)
- Atique U. Ahmed (ORCID: https://orcid.org/0000-0003-4795-0188)
- Craig Horbinski (ORCID: https://orcid.org/0000-0001-8340-9992)
- Víctor A. Arrieta (ORCID: https://orcid.org/0000-0003-2738-9741)
- Catalina Lee-Chang (ORCID: https://orcid.org/0000-0002-7675-2124)
- Crismita Dmello (ORCID: https://orcid.org/0000-0002-1688-9663)
- Levi van Hijfte (ORCID: https://orcid.org/0000-0002-1402-6784)
- Kwang‐Soo Kim (ORCID: https://orcid.org/0000-0001-7535-7088)
- Adam M. Sonabend (ORCID: https://orcid.org/0000-0002-8347-1945)
- Vivekanudeep Karri (ORCID: https://orcid.org/0000-0001-7663-1624)
- Dieter Henrik Heiland (ORCID: https://orcid.org/0000-0002-9258-3033)
- Karl J. Habashy (ORCID: https://orcid.org/0000-0003-1210-378X)
- Ragini Yeeravalli
- Ningjia Zhou
- Lu Wang (ORCID: https://orcid.org/0000-0002-0073-0666)
- Li Chen (ORCID: https://orcid.org/0000-0002-5127-5878)
- Heba Ali (ORCID: https://orcid.org/0000-0001-5535-7638)
- Snehasis Mishra (ORCID: https://orcid.org/0000-0003-1809-6306)
- Xiao Song
- Joseph Duffy
- Yalu Zhou
- Rima Tulaiha
Institutions
- Northwestern University (US)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
- Assiut University (EG)
Publication Details
- Journal
- Neuro-Oncology
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1093/neuonc/noaf227
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00