Exploring the Pharmacological Potential of Achyranthes aspera (Latzeera): A Complete Investigation of its Anticancer, Anti-Microbial and Antioxidant Activities

Background: A medicinal herb called Achyranthes aspera has been used for centuries to treat a wide range of illnesses.By assessing its antineoplastic, anti-microbial and antioxidant properties.This study sought to thoroughly explore Achyranthes aspera pharmacological potential.Materials and Methods: Antibacterial activity against a panel of bacterial strains was assessed using the disc diffusion method.To ascertain cell viability in cancer cell lines, anti-cancer activity was assessed using the MTT assay.The antioxidant activity of the plant extract was assessed by its capacity to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals.Results: Achyranthes aspera extract showed encouraging antibacterial efficacy against specific bacterial strains, however not as strong as the common antibiotic, ciprofloxacin.The MTT assay indicated possible anti-cancer efficacy by showing a notable dose-dependent reduction in cancer cell lines' cell viability.Through the scavenging of free radicals, the extract from Achyranthes aspera also demonstrated strong antioxidant activity.Conclusion: The pharmacological potential of Achyranthes aspera is strongly supported by this investigation, confirming its historic use in treating a variety of illnesses.Promising antioxidant, antimicrobial and anti-cancer properties were demonstrated by the plant extract.In order to determine the bioactive components, clarify the underlying mechanisms of action, assess the protection and efficacy of Achyranthes aspera extracts in preclinical, clinical contexts, these findings call for additional research.

Authors

Publication Details

Journal
Pharmacognosy Research
Published
2025-09-29
DOI
https://doi.org/10.5530/pres.20252314
Primary Topic
Natural Antidiabetic Agents Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Exploring the Pharmacological Potential of Achyranthes aspera (Latzeera): A Complete Investigation of its Anticancer, Anti-Microbial and Antioxidant Activities

Biswajit Dash, Aftab Alam, Tajinder Kaur, Yashna Bawa et al.
Pharmacognosy Research
Natural Antidiabetic Agents Studies
article

Exploring the Pharmacological Potential of Achyranthes aspera (Latzeera): A Complete Investigation of its Anticancer, Anti-Microbial and Antioxidant Activities

Biswajit Dash, Aftab Alam, Tajinder Kaur, Yashna Bawa, Shivani Devi, Varsha Chauhan, Ayush Garg, Ankita Sharma, Ashish Sarkar, Arijit Chaudhuri
article en

Abstract

Background: A medicinal herb called Achyranthes aspera has been used for centuries to treat a wide range of illnesses.By assessing its antineoplastic, anti-microbial and antioxidant properties.This study sought to thoroughly explore Achyranthes aspera pharmacological potential.Materials and Methods: Antibacterial activity against a panel of bacterial strains was assessed using the disc diffusion method.To ascertain cell viability in cancer cell lines, anti-cancer activity was assessed using the MTT assay.The antioxidant activity of the plant extract was assessed by its capacity to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals.Results: Achyranthes aspera extract showed encouraging antibacterial efficacy against specific bacterial strains, however not as strong as the common antibiotic, ciprofloxacin.The MTT assay indicated possible anti-cancer efficacy by showing a notable dose-dependent reduction in cancer cell lines' cell viability.Through the scavenging of free radicals, the extract from Achyranthes aspera also demonstrated strong antioxidant activity.Conclusion: The pharmacological potential of Achyranthes aspera is strongly supported by this investigation, confirming its historic use in treating a variety of illnesses.Promising antioxidant, antimicrobial and anti-cancer properties were demonstrated by the plant extract.In order to determine the bioactive components, clarify the underlying mechanisms of action, assess the protection and efficacy of Achyranthes aspera extracts in preclinical, clinical contexts, these findings call for additional research.

Pharmacognosy ResearchVol. 17(4)
Openalex Percentile: Top 64%
Natural Antidiabetic Agents Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.