Zinc finger GATA-like protein 1 regulates apoptosis and phenotypic transformation via protein kinase B pathway in human vascular smooth muscle cells

ZGLP1 knockdown induces apoptosis through the AKT pathway, and also induces the phenotypic transformation of HASMCs. ZGLP1 is a potential therapeutic target for intracranial aneurysm and deserves further research.

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Publication Details

Journal
Neuroreport
Published
2025-09-24
DOI
https://doi.org/10.1097/wnr.0000000000002217
Primary Topic
Moyamoya disease diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Zinc finger GATA-like protein 1 regulates apoptosis and phenotypic transformation via protein kinase B pathway in human vascular smooth muscle cells

Renhui Yi, Zhaobin Zeng, Zhihao Zhang, Shuai Yuan et al.
Neuroreport
Moyamoya disease diagnosis and treatment
article

Zinc finger GATA-like protein 1 regulates apoptosis and phenotypic transformation via protein kinase B pathway in human vascular smooth muscle cells

Renhui Yi, Zhaobin Zeng, Zhihao Zhang, Shuai Yuan, Hongquan Zhu, Heng Zhou, JianGuo Zhong, Haibin Wang
article en

Abstract

ZGLP1 knockdown induces apoptosis through the AKT pathway, and also induces the phenotypic transformation of HASMCs. ZGLP1 is a potential therapeutic target for intracranial aneurysm and deserves further research.

NeuroreportVol. 36(16)
Henan Psychiatric Hospital (CN), Gannan Medical University (CN), First Affiliated Hospital of Gannan Medical University (CN)
Openalex Percentile: Top 60%
Moyamoya disease diagnosis and treatment
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