Substantiation of the composition and technology of production of medicinal lollipops with CO2-extracts of ginger rhizomes and dandelion roots

Introduction. It is known that the combination of therapeutic physical activity and a properly selected diet gives positive results if the patient's goal is to return his weight to normal in terms of age, height and general constitution. However, dietary adjustments are not always sufficient to achieve weight loss. The patterns of individual metabolism that have become entrenched over many years of malnutrition continue to irrationally distribute metabolic products even with diet correction. This undesirable phenomenon can be corrected by introducing supplements into the diet that accelerate metabolism and promote the elimination of undesirable metabolites. Objective. Development of the composition and technology of medicinal lollipops with CO2 extracts of ginger rhizomes and dandelion roots, which will be offered for use in gastroenterology to accelerate metabolism (weight loss products). To achieve this goal, the following tasks were solved: the need to create medicinal lollipops was justified; the selection of active and auxiliary substances for the production of lollipops was carried out; the optimal technological scheme of production was selected; test samples of lollipops were made; their quality was assessed. Material and methods. The studies were conducted according to the methods of the State Pharmacopoeia (SP) XIV and XV editions. In the experimental studies, biologically active substances and auxiliary substances obtained from manufacturers with the corresponding analysis protocols according to the requirements of ND were used. CO2-extract of ginger rhizomes and dandelion roots produced at the enterprise Biotsevtika LLC in Dedovsk, Moscow Region were used as the main biologically active substance. Organoleptic properties were assessed subjectively, by checking the appearance, smell, presence of foreign impurities, homogeneity. Both raw materials and finished products were subjected to these tests in accordance with the regulatory documentation. Results. The composition and technology of medicinal lollipops with CO2-extract of ginger rhizomes and dandelion roots have been developed, the feasibility of which has been confirmed by expert assessments (organoleptic properties), and the technological properties have also been studied. A technological scheme for the production of medicinal lollipops with CO2-extract of ginger rhizomes and dandelion roots has been developed. Conclusion. Lozenges, as a dosage form, have enough advantages over other dosage forms for internal use, due to which it is optimally suited for the creation of a dosage form for use in gastroenterology, in which it is easy to include the CO2-extract we offer as active substances. The technological studies conducted allowed us to develop the composition and technology of medicinal lozenges with CO2-extract of ginger and dandelion roots. Technological tests of the proposed lozenges were carried out, as a result of which positive consumer properties of this dosage form were revealed