Blood Cultures Contain Populations of Genetically Diverse <i>Candida albicans</i> Strains that May Differ in Echinocandin Tolerance and Fitness
BCs in some patients are comprised of diverse C. albicans populations not recognized by the clinical lab, rather than single strains. Clinical relevance of C. albicans diversity and echinocandin tolerance merits further investigation.
Authors
- Christopher L. Dupont (ORCID: https://orcid.org/0000-0002-0896-6542)
- Hassan Badrane (ORCID: https://orcid.org/0009-0009-7412-0199)
- Darren Abbey (ORCID: https://orcid.org/0000-0003-4667-8004)
- M. Hong Nguyen (ORCID: https://orcid.org/0000-0003-2065-3239)
- Josh L. Espinoza (ORCID: https://orcid.org/0000-0003-3447-3845)
- C. J. Clancy (ORCID: https://orcid.org/0000-0003-1750-4005)
- Giuseppe Fleres (ORCID: https://orcid.org/0000-0002-2332-8960)
- Anthony Newbrough
- Eileen Driscoll (ORCID: https://orcid.org/0000-0003-3673-4228)
- Akila Mansour
- Binghua Hao
- Shaoji Cheng
Institutions
- J. Craig Venter Institute (US)
- University of Minnesota (US)
- University of Pittsburgh (US)
- VA Pittsburgh Healthcare System (US)
- University of Pittsburgh Medical Center (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1093/infdis/jiaf495
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00