Preparation of α,β,γ,γ-tetrasubstituted α,β-unsaturated γ-lactams <i>via</i> a tandem or one-pot oxidative Ritter reaction/Knoevenagel condensation
An efficient synthesis of α,β,γ,γ-tetrasubstituted α,β-unsaturated γ-lactams has been developed through a tandem or one-pot oxidative Ritter reaction/Knoevenagel condensation of functionalized nitriles and 2-arylketones for the first time.
Authors
- Yue‐Hong Hu
- Zhang‐Yan Gan
- Chengcheng Yu (ORCID: https://orcid.org/0000-0003-3595-0017)
- Xiao‐Ming Zhang (ORCID: https://orcid.org/0000-0002-9294-9672)
- Fu‐Min Zhang (ORCID: https://orcid.org/0000-0001-5578-1148)
- Meng-En Chen
- Yuting Chen (ORCID: https://orcid.org/0000-0003-0436-8876)
- J. Mo (ORCID: https://orcid.org/0009-0001-2285-7019)
Institutions
- Lanzhou University (CN)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ob01300c
- Primary Topic
- Chemical Synthesis and Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00