Lung Cancer Screening in Cancer Survivors vs Those Without a History of Cancer
In this cohort study of LCS-screened individuals, cancer survivors were more likely to be older and formerly smoked and had slightly more comorbidities compared with individuals without prior cancer. Although rates of positive LDCT findings were similar, these findings suggest that the lung CDR may be higher in cancer survivors vs those without prior cancer and should be evaluated in larger studies. The complex relationship between cancer survivorship and the risk of second primary lung cancer underscores both the challenges and the opportunities for preventive care, such as LCS, in this population.
Authors
- Danielle D. Durham (ORCID: https://orcid.org/0000-0002-8871-589X)
- Louise M. Henderson (ORCID: https://orcid.org/0000-0001-8356-9267)
- Lindsay Lane (ORCID: https://orcid.org/0000-0003-4361-3109)
- Thad Benefield (ORCID: https://orcid.org/0000-0002-4218-3330)
- Kevin A Fiscella (ORCID: https://orcid.org/0000-0003-3613-8012)
- Supriya G. Mohile (ORCID: https://orcid.org/0000-0003-0867-327X)
- M. Patricia Rivera (ORCID: https://orcid.org/0000-0003-3827-5010)
Institutions
- University of North Carolina at Chapel Hill (US)
- University of Rochester Medical Center (US)
- UNC Lineberger Comprehensive Cancer Center
- University of Rochester (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.35000
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Cancer Institute
- National Center for Advancing Translational Sciences