A case report on the treatment of autoimmune hemolytic anemia after CBT by daratumumab in a mucopolysaccharidosis type III patient

This report discusses a child with MPS III, a rare disorder characterized by complex and varied phenotypes, including distinctive facial features, short stature, cognitive regression, varying degrees of skeletal deformities, and hepatosplenomegaly. The patient has autoimmune hemolysis after umbilical cord blood transplantation. For patients who do not respond to rituximab and gamma globulin, daratumumab may be considered.

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Publication Details

Journal
Medicine
Published
2025-09-26
DOI
https://doi.org/10.1097/md.0000000000044874
Primary Topic
Blood groups and transfusion
Type
article
Field-Weighted Citation Impact
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article

A case report on the treatment of autoimmune hemolytic anemia after CBT by daratumumab in a mucopolysaccharidosis type III patient

Li Xu, Z. Christine Bian
Medicine
Blood groups and transfusion
article

A case report on the treatment of autoimmune hemolytic anemia after CBT by daratumumab in a mucopolysaccharidosis type III patient

Li Xu, Z. Christine Bian
article en

Abstract

This report discusses a child with MPS III, a rare disorder characterized by complex and varied phenotypes, including distinctive facial features, short stature, cognitive regression, varying degrees of skeletal deformities, and hepatosplenomegaly. The patient has autoimmune hemolysis after umbilical cord blood transplantation. For patients who do not respond to rituximab and gamma globulin, daratumumab may be considered.

MedicineVol. 104(39)
Bengbu Medical College (CN), Anhui Provincial Hospital (CN)
Openalex Percentile: Top 65%
Blood groups and transfusion
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