Scutellarein attenuates alcohol-induced hepatocyte injury by modulating NF-κB and NRF2 signaling pathways
SCU protects hepatocytes against alcohol-induced injury by modulating apoptosis, inflammation, and oxidative stress through regulation of nuclear factor kappa-B and nuclear factor erythroid 2-related factor 2 signaling pathways. These findings highlight its potential as a promising hepatoprotective agent.
Authors
- Minghua Cao (ORCID: https://orcid.org/0009-0004-9706-906X)
- Ziqi Sui (ORCID: https://orcid.org/0000-0002-6764-8608)
- Shuxia Shen
Institutions
- Zhejiang Chinese Medical University (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
Publication Details
- Journal
- Medicine
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1097/md.0000000000044506
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00