Therapeutic effect and mechanism of sivelestat sodium on acute lung injury: A randomized controlled trial
Sivelestat sodium can improve lung function, correct PaO2/FiO2, and promote rehabilitation in patients with acute lung injury, which may be related to the regulation of NLRP6, ICAM-1, and other inflammatory factors.
Authors
- Qiang Ji (ORCID: https://orcid.org/0000-0002-1769-6118)
- Yaqing Zhou (ORCID: https://orcid.org/0000-0003-1887-872X)
- Aiming Liu (ORCID: https://orcid.org/0000-0002-5937-6278)
- Haiyan Wang (ORCID: https://orcid.org/0009-0000-6582-9301)
- Kang Xu (ORCID: https://orcid.org/0000-0002-6946-8635)
- Guihua Chen (ORCID: https://orcid.org/0000-0001-9776-8515)
- Ying Wang (ORCID: https://orcid.org/0009-0002-4274-7412)
- Xuehua Pu
- Zunguo Pu
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Second People's Hospital of NanTong (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- Second Affiliated Hospital of Nantong University
- Nanjing Medical University (CN)
Publication Details
- Journal
- Medicine
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1097/md.0000000000042703
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00