Pharmacokinetic Analysis of Compounds Instilled into the Mouse Lung: Study with <i>In Vivo</i> Electron Spin Resonance Spectroscopy and Nitroxyl Spin Probes as Model Drugs
The differences in pharmacokinetic behavior in lungs could be examined <i>in vivo</i> among model compounds with different charge states. <i>In vivo</i> ESR spectroscopy is a powerful tool for the <i>in vivo</i> analysis of pulmonary pharmacokinetics, in combination with nitroxyl probes as model drugs.
Authors
- Hideo Utsumi (ORCID: https://orcid.org/0000-0001-6992-1658)
- Shoko Okazaki (ORCID: https://orcid.org/0000-0002-7071-0628)
- Jin‐Yi Han (ORCID: https://orcid.org/0000-0003-2074-4472)
Institutions
- Kyushu University (JP)
- University of Shizuoka (JP)
- Sojo University (JP)
- Keimyung University Dongsan Medical Center (KR)
- Keimyung University (KR)
Publication Details
- Journal
- Journal of Aerosol Medicine and Pulmonary Drug Delivery
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1177/19412711251379678
- Primary Topic
- Electron Spin Resonance Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00