Three New Phenyl Ether Derivatives From the Deep‐Sea‐Derived Fungus <i>Aspergillus</i> sp. SCSIO 41230
Three new phenyl ether derivatives (1-3) and 11 known compounds (4-14) were isolated from the deep-sea-derived fungus Aspergillus sp. SCSIO 41230. The structures of the new compounds were elucidated by analysis of the nuclear magnetic resonance (NMR), high-resolution electrospray ionization mass spectrometry, and NMR calculations. The bioassays indicated that compound 6 showed weak cytotoxic activity against PC-3 and 22Rv1 cells, and compound 4 exhibited antibacterial activity against methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration value of 4.13 µg/mL.
Authors
- Bin Yang (ORCID: https://orcid.org/0000-0003-4748-2484)
- Yonghong Liu (ORCID: https://orcid.org/0000-0003-4550-7924)
- Xiao‐Yong Zhang (ORCID: https://orcid.org/0000-0001-8965-1077)
- Xuefeng Zhou (ORCID: https://orcid.org/0000-0001-9601-4869)
- S. Y. Xu (ORCID: https://orcid.org/0000-0002-1828-1168)
- Juan Gao (ORCID: https://orcid.org/0000-0003-3252-3474)
- Juan Liu (ORCID: https://orcid.org/0000-0002-8239-2284)
- Yanchun He (ORCID: https://orcid.org/0000-0002-5932-3627)
Institutions
- South China Agricultural University (CN)
- South China Sea Institute Of Oceanology (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Chemistry & Biodiversity
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1002/cbdv.202502248
- Citations
- 1
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.39