Impact of Kangaroo Mother Care on oxygen saturation histogram profiles among preterm infants: A prospective comparative study

BackgroundPreterm infants often experience oxygen saturation (SpO₂) instability due to immature respiratory control. While Kangaroo Mother Care (KMC) is known to improve cardiorespiratory stability, its impact on detailed SpO₂ dynamics using histogram analysis has not been well studied.MethodsIn this prospective observational study, 120 paired sessions of KMC and off-KMC were analyzed in preterm infants (26 + 0 to 32 + 6 weeks gestation) admitted to a tertiary neonatal unit. Each session involved continuous SpO₂ monitoring using Masimo Radical-7 oximeters. The primary outcome was the percentage of time with SpO₂ ≤90%. Secondary outcomes included subgroup analyses by postmenstrual age (PMA) and respiratory support status.ResultsInfants spent less time with SpO₂ ≤90% during KMC (median 10%, IQR: 7-17) compared to off-KMC (12%, IQR: 8-18), although not statistically significant (<i>p</i> = 0.06). A significant reduction was noted in infants on room air (median 9% vs 11%; <i>p</i> = 0.01). No significant difference was observed in those on CPAP, HFNC, or NIPPV. Infants with PMA >34 weeks showed an improvement in histogram trend during KMC, which was not statistically significant (<i>p</i> = 0.06).ConclusionsOverall, KMC showed a trend towards improved oxygen saturation patterns, although this was not statistically significant. Among stable preterm infants on room air without respiratory support, KMC was associated with a significant improvement.