Ecthyma Gangrenosum-Like Lesion in a Patient With a Leukocyte Adhesion Defect: Pseudomonas aeruginosa, Staphylococcus aureus, and a Rare Agent, Fusarium

<i>Fusarium</i> species can cause serious infections, including superficial and invasive ones. In immunocompromised individuals, they can cause skin infections such as ecthyma gangrenosum and disseminated disease through lymphatic spread. In this case report, we present a nine-year-old girl with ecthyma gangrenosum whose primary disease was a leukocyte adhesion defect (LAD). She developed a burn on her right lower extremity after spilling hot tea. <i>Pseudomonas aeruginosa, Staphylococcus aureus,</i> and <i>Fusarium</i> spp<i>.</i> were isolated from a wound culture taken from her ankle. While <i>Pseudomonas aeruginosa</i> is generally the causative agent of ecthyma gangrenosum, <i>Fusarium</i> species can also be encountered in patients with neutropenia or neutrophil dysfunction. It should be noted that <i>Fusarium</i> species, a rare mold pathogen, can also cause serious skin infections in immunocompromised patients, particularly after burns.

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Journal
Cureus
Published
2025-09-30
DOI
https://doi.org/10.7759/cureus.93580
Primary Topic
Infections and bacterial resistance
Type
article
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article

Ecthyma Gangrenosum-Like Lesion in a Patient With a Leukocyte Adhesion Defect: Pseudomonas aeruginosa, Staphylococcus aureus, and a Rare Agent, Fusarium

Asena Ünal, Arbil Açıkalın, Mahir Serbes, Derya Alabaz et al.
Cureus
Infections and bacterial resistance
article

Ecthyma Gangrenosum-Like Lesion in a Patient With a Leukocyte Adhesion Defect: Pseudomonas aeruginosa, Staphylococcus aureus, and a Rare Agent, Fusarium

Asena Ünal, Arbil Açıkalın, Mahir Serbes, Derya Alabaz, Özlem Özgür Gündeşli̇oğlu, Dilek Özcan, Ümmühan Çay, Fatma Tuğba Çetin
article en

Abstract

<i>Fusarium</i> species can cause serious infections, including superficial and invasive ones. In immunocompromised individuals, they can cause skin infections such as ecthyma gangrenosum and disseminated disease through lymphatic spread. In this case report, we present a nine-year-old girl with ecthyma gangrenosum whose primary disease was a leukocyte adhesion defect (LAD). She developed a burn on her right lower extremity after spilling hot tea. <i>Pseudomonas aeruginosa, Staphylococcus aureus,</i> and <i>Fusarium</i> spp<i>.</i> were isolated from a wound culture taken from her ankle. While <i>Pseudomonas aeruginosa</i> is generally the causative agent of ecthyma gangrenosum, <i>Fusarium</i> species can also be encountered in patients with neutropenia or neutrophil dysfunction. It should be noted that <i>Fusarium</i> species, a rare mold pathogen, can also cause serious skin infections in immunocompromised patients, particularly after burns.

CureusVol. 17(9)
Cukurova University (TR)
Openalex Percentile: Top 77%
Infections and bacterial resistance
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