Assessment of frailty in patients with advanced chronic kidney disease, and the role of microvesicles: A single-center study
Frailty is highly prevalent in patients with advanced CKD. Although we still do not know in depth the mechanisms involved in frailty, to our knowledge this is the first study that links cMVs and frailty in patients with advanced CKD. In our opinion it could be explored as a good biomarker or therapeutic target in advanced CKD.
Authors
- Rafael Ramírez‐Chamond
- Juan Arévalo‐Serrano (ORCID: https://orcid.org/0000-0003-2563-7860)
- Diego Rodrı́guez-Puyol (ORCID: https://orcid.org/0000-0002-9125-9311)
- Julia Carracedo (ORCID: https://orcid.org/0000-0002-8422-812X)
- Patricia Martínez‐Miguel (ORCID: https://orcid.org/0000-0002-4544-7581)
- Rocío Gimena Muñoz (ORCID: https://orcid.org/0000-0002-2827-595X)
- Sushrut S. Waikar (ORCID: https://orcid.org/0000-0003-4004-326X)
- María Pérez Fernández
- María del Mar Rodríguez San Pedro
- Gemma Valera Arévalo
Institutions
- Boston Medical Center (US)
- Universidad de Alcalá (ES)
- Instituto Cajal (ES)
- Research Institute Hospital 12 de Octubre (ES)
- Hospital Universitario Príncipe de Asturias (ES)
- Instituto Ramón y Cajal de Investigación Sanitaria (ES)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1371/journal.pone.0332653
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00