Severe autoimmune hemolytic anemia in ICU: a place for emergency plasma exchange? A French multicenter retrospective study
In this large ICU cohort, severe AIHA was associated with high mortality, driven by organ failure rather than anemia severity. PlEx are associated with survival, suggesting its potential role as a bridge to immunosuppressive therapy in selected cases. Prospective studies are needed to confirm these findings.
Authors
- Tomas Urbina (ORCID: https://orcid.org/0000-0002-3745-9427)
- Muriel Fartoukh
- Antoine Vieillard Baron
- Judith Leblanc (ORCID: https://orcid.org/0000-0002-0323-6671)
- Wulfran Bougouin (ORCID: https://orcid.org/0000-0002-1821-7713)
- O. Fain (ORCID: https://orcid.org/0000-0002-1974-3870)
- Delphine Gobert
- Frédéric Pène (ORCID: https://orcid.org/0000-0003-3639-3849)
- Louaï Missri
- Bruno Mégarbane (ORCID: https://orcid.org/0000-0002-2522-2764)
- Maxens Decavèle (ORCID: https://orcid.org/0000-0003-3552-5053)
- Hafid Ait‐Oufella (ORCID: https://orcid.org/0000-0002-2955-0183)
- Djillali Annane (ORCID: https://orcid.org/0000-0001-6805-8944)
- Charles Damoisel (ORCID: https://orcid.org/0000-0003-2301-9700)
- Alain Combes (ORCID: https://orcid.org/0000-0002-6030-3957)
- Khalil Chaïbi (ORCID: https://orcid.org/0000-0001-9106-586X)
- Xavier Monnet (ORCID: https://orcid.org/0000-0001-6820-2678)
- Emmanuel Weiss (ORCID: https://orcid.org/0000-0002-2854-9607)
- Vincent Bonny (ORCID: https://orcid.org/0000-0002-8996-8426)
- Jérémie Joffre
- Nicolas de Prost
- Jéan‐François Timsit
- J J Bernier
- Lara Zafrani
- Éric Maury (ORCID: https://orcid.org/0000-0002-7287-8694)
- Jean‐Damien Ricard
- Jean‐Luc Baudel
- Sacha Seksik
- Jean-Baptiste Destival
Institutions
- Inserm (FR)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Saint-Antoine (FR)
- Paris Cardiovascular Research Center (FR)
- Institut Pierre Louis d‘Épidémiologie et de Santé Publique (FR)
- Centre de Recherche Saint-Antoine (FR)
- Hôpital Privé Jacques Cartier (FR)
Publication Details
- Journal
- Critical Care
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1186/s13054-025-05601-6
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Assistance publique-Hôpitaux de Paris