Does TXA reduce total volume of 24-hour blood products transfused in post-traumatic hemorrhage in a resource-constrained setting:Secondary analysis of a prospective cohort trauma study in South Africa.
In a cohort of adult trauma patients with major hemorrhage, there was no difference in total blood volume transfused within the first 24 h between patients who received tranexamic acid compared to those who did not.
Authors
- Joseph K. Maddry (ORCID: https://orcid.org/0000-0002-8341-4182)
- Hendrick J. Lategan
- Willem Stassen (ORCID: https://orcid.org/0000-0002-1486-4446)
- Julia Dixon (ORCID: https://orcid.org/0000-0002-9229-2658)
- Chelsea Dymond
- Janette Verster (ORCID: https://orcid.org/0000-0002-1273-5456)
- Craig Wylie (ORCID: https://orcid.org/0000-0003-2168-4838)
- Nee‐Kofi Mould‐Millman (ORCID: https://orcid.org/0000-0003-4303-6903)
- Steven Gremel Schauer (ORCID: https://orcid.org/0000-0002-2322-5216)
- Lani Finck
- Shaheem de Vries (ORCID: https://orcid.org/0000-0003-3986-1652)
- Mengli Xiao (ORCID: https://orcid.org/0000-0003-4974-3588)
- George Oosthuizen
- EpiC Study Site Collaborators
Institutions
- Brooke Army Medical Center (US)
- St. Joseph Hospital (US)
- Western Cape Department of Health (ZA)
- Colorado School of Public Health (US)
- University of Cape Town (ZA)
- Stellenbosch University (ZA)
- Right to Care (ZA)
- University of Colorado Anschutz Medical Campus (US)
- Joint Base San Antonio (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- International Journal of Emergency Medicine
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1186/s12245-025-00972-7
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Defense Health Agency