Investigation of the toxic dose of ingested delta-8 tetrahydrocannabinol among young children
Despite limitations of NPDS data and inconsistent quality control and labeling of Δ8THC products, the findings of our study are similar to those previously described for delta-9 tetrahydrocannabinol ingestions among young children. We found that a 1.7 mg/kg dose cutoff value for Δ8THC had a high sensitivity for identifying severe or prolonged toxicity associated with Δ8THC ingestions among children < 6 years old; however, it was associated with a high number of false positives.
Authors
- Jaahnavi Badeti (ORCID: https://orcid.org/0000-0002-4018-281X)
- Gary A. Smith (ORCID: https://orcid.org/0000-0001-5838-8982)
- Leah K. Middelberg (ORCID: https://orcid.org/0000-0002-5005-2939)
- Natalie I. Rine (ORCID: https://orcid.org/0000-0003-1912-0697)
- Christopher E. Gaw (ORCID: https://orcid.org/0000-0002-2847-6372)
- Hannah L. Hays (ORCID: https://orcid.org/0009-0006-5643-829X)
- Ryan S. Garay
Institutions
- Nationwide Children's Hospital (US)
- George Washington University (US)
- National Center for Injury Prevention and Control (US)
- Université Bourgogne Franche-Comté (FR)
- The Ohio State University (US)
- Nationwide Mutual Insurance Company (United States) (US)
Publication Details
- Journal
- Injury Epidemiology
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1186/s40621-025-00617-6
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00