Whole-Genome Sequencing of Hepatitis B Virus Genotypes E and A in Zambia Reveals Limited Viral Diversity in HIV Coinfection
HBV gtE exhibited distinct substitution patterns compared with gtA, and HBV/HIV was associated with reduced HBV sequence diversity, consistent with impaired immune pressure.
Authors
- Georg M. Lauer (ORCID: https://orcid.org/0000-0002-9792-4271)
- Aleksei Suslov (ORCID: https://orcid.org/0000-0002-4774-9399)
- Guy Muula
- Michael J. Vinikoor (ORCID: https://orcid.org/0000-0002-3862-7795)
- Anja Voges
- Kalo Musukuma (ORCID: https://orcid.org/0000-0002-3620-6065)
- Raymond T. Chung (ORCID: https://orcid.org/0000-0001-7587-718X)
- Markus H. Heim (ORCID: https://orcid.org/0000-0002-7523-4894)
- Paul Kelly (ORCID: https://orcid.org/0000-0003-0844-6448)
- Gilles Wandeler (ORCID: https://orcid.org/0000-0002-5278-8763)
- Nadia Alatrakchi (ORCID: https://orcid.org/0000-0001-7600-564X)
- Robert E. Schwartz (ORCID: https://orcid.org/0000-0002-5417-5995)
- Andreas Walker (ORCID: https://orcid.org/0000-0002-8736-0863)
- Edford Sinkala (ORCID: https://orcid.org/0000-0002-5678-4540)
- Taonga Musonda (ORCID: https://orcid.org/0009-0008-9533-448X)
- Samuel Bosomprah (ORCID: https://orcid.org/0000-0002-2826-3887)
- Jörg Timm (ORCID: https://orcid.org/0000-0001-7799-3045)
- Eleftherios Michailidis (ORCID: https://orcid.org/0000-0002-9907-4346)
- Annie Kanunga
- Nadine Lübke (ORCID: https://orcid.org/0000-0003-3820-7915)
- Duyen Bao Le
- Martin Feuerherd (ORCID: https://orcid.org/0000-0002-5272-6503)
- Debika Bhattacharya (ORCID: https://orcid.org/0000-0002-2136-7763)
- Bright Nsokolo (ORCID: https://orcid.org/0000-0002-9338-0350)
- Carolyn Chibundi
- Maximillian Damagnez
- Given Bwalya
Institutions
- University of Bern (CH)
- Centre for Infectious Disease Research in Zambia (ZM)
- Bern University of Applied Sciences (CH)
- University of Ghana (GH)
- Emory University (US)
- University of California, Los Angeles (US)
- Queen Mary University of London (GB)
- University of Basel (CH)
- Cornell University (US)
- University Hospital of Basel (CH)
- Lusaka Apex Medical University (ZM)
- University of Alabama at Birmingham (US)
- University of Zambia (ZM)
- Massachusetts General Hospital (US)
- Department of Biomedicine Basel (CH)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-09-27
- DOI
- https://doi.org/10.1093/ofid/ofaf616
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00