An Imitation Too Perfect: Isolated Neurosarcoidosis Mimicking Spheno-Orbital Meningioma With Hyperostosis

We report a rare case of isolated neurosarcoidosis presenting as a spheno-orbital mass with hyperostosis of the sphenoid wing, initially misdiagnosed as a meningioma. Neurosarcoidosis may manifest as dural-based lesions that mimic tumors radiologically; however, hyperostosis, a hallmark of meningiomas, is usually absent. This unusual presentation causes diagnostic confusion. This case highlights the diagnostic challenges when sarcoidosis mimics meningiomas, particularly in the presence of hyperostosis. Awareness of such atypical presentations is crucial for accurate diagnosis and appropriate management.

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Publication Details

Journal
Cureus
Published
2025-09-30
DOI
https://doi.org/10.7759/cureus.93591
Primary Topic
Sarcoidosis and Beryllium Toxicity Research
Type
article
Field-Weighted Citation Impact
0.00
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article

An Imitation Too Perfect: Isolated Neurosarcoidosis Mimicking Spheno-Orbital Meningioma With Hyperostosis

P. Desclée, Lina Daoud, Patrice Finet
Cureus
Sarcoidosis and Beryllium Toxicity Research
article

An Imitation Too Perfect: Isolated Neurosarcoidosis Mimicking Spheno-Orbital Meningioma With Hyperostosis

P. Desclée, Lina Daoud, Patrice Finet
article en

Abstract

We report a rare case of isolated neurosarcoidosis presenting as a spheno-orbital mass with hyperostosis of the sphenoid wing, initially misdiagnosed as a meningioma. Neurosarcoidosis may manifest as dural-based lesions that mimic tumors radiologically; however, hyperostosis, a hallmark of meningiomas, is usually absent. This unusual presentation causes diagnostic confusion. This case highlights the diagnostic challenges when sarcoidosis mimics meningiomas, particularly in the presence of hyperostosis. Awareness of such atypical presentations is crucial for accurate diagnosis and appropriate management.

CureusVol. 17(9)
UCLouvain (BE)
Openalex Percentile: Top 66%
Sarcoidosis and Beryllium Toxicity Research
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