LONG-TERM AFFECTIVE DISORDERS AFTER THROMBECTOMY FOR THROMBOTIC OCCLUSION: AN OBJECTIVE ASSESSMENT

The study presents an analysis of affective disorders in patients who underwent thrombectomy for thrombotic occlusion during the remote postoperative period. Objective: to determine the specific features of the affective sphere in patients who underwent thrombectomy for thrombotic occlusion. Between 2023 and 2024, a prospective study was conducted at the Center of Endovascular Neurosurgery of the Kyiv City Clinical Hospital No. 1 (Kyiv, Ukraine), involving 96 patients who had experienced ischemic stroke and subsequently underwent surgical thrombectomy for thrombotic occlusion. The assessment of affective sphere characteristics in the selected cohort was carried out, in particular, during the remote postoperative period (30–35 days after surgery) using the Hamilton Anxiety Rating Scale (HARS, G. S. Bruss et al., 1994), the Hamilton Depression Rating Scale (HDRS, B. V. Mykhailov et al., 2014), and the Young Mania Rating Scale (YMRS, R. C. Young et al., 1978). The obtained results were compared with patients’ medical history data and stroke severity assessment according to the NIHSS and ASPECTS scales. The severity and clinical manifestations of affective disorders in the selected cohort of patients were objectified and determined: they were predominantly characterized by high levels of anxiety and depression, low levels of manic symptomatology, and isolated cases of mixed affective states, the intensity of which fluctuated throughout the day. These conditions were marked by semiotic features of the psycho-organic register, indicating the predominant role of central nervous system impairment in the etiopathogenesis of the observed phenomena. The cohort of patients who underwent thrombectomy for thrombotic occlusion has a number of features that determine specific mechanisms for the formation of secondary mental disorders and determine the relevance of further research.