Development of a retinal pathology classification model using transfer learning and open datasets

The retina is a multilayer structure that perceives and transmits visual stimuli to the brain via the optic nerve; however, its complex structure makes it vulnerable to damage. Optical coherence tomography (OCT) is the gold standard for diagnosing retinal pathologies. This study aimed to develop a deep learning model for the classification of retinal pathologies based on OCT data. The study design included the use of transfer learning and training a model with a ResNet-50 architecture on three open datasets containing over 110.000 OCT images and 10 retinal condition classes, including normal and 10 pathological conditions. As a result, the model demonstrated a high classification accuracy of 95 %. Thus, transfer learning and significant dataset expansion provide high classification model accuracy. The study also highlights that open access to data significantly impacts the development of artificial intelligence technologies in healthcare.

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Publication Details

Journal
Cybernetics and Physics
Published
2025-09-30
DOI
https://doi.org/10.35470/2226-4116-2025-14-2-95-102
Primary Topic
Retinal Imaging and Analysis
Type
article
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article

Development of a retinal pathology classification model using transfer learning and open datasets

Anton V. Prisyazhnyuk, K. D. Aksenov, Andrey Krasov, V. V. Myasnikova et al.
Cybernetics and Physics
Retinal Imaging and Analysis
article

Development of a retinal pathology classification model using transfer learning and open datasets

Anton V. Prisyazhnyuk, K. D. Aksenov, Andrey Krasov, V. V. Myasnikova, L. E. Aksenova
article en

Abstract

The retina is a multilayer structure that perceives and transmits visual stimuli to the brain via the optic nerve; however, its complex structure makes it vulnerable to damage. Optical coherence tomography (OCT) is the gold standard for diagnosing retinal pathologies. This study aimed to develop a deep learning model for the classification of retinal pathologies based on OCT data. The study design included the use of transfer learning and training a model with a ResNet-50 architecture on three open datasets containing over 110.000 OCT images and 10 retinal condition classes, including normal and 10 pathological conditions. As a result, the model demonstrated a high classification accuracy of 95 %. Thus, transfer learning and significant dataset expansion provide high classification model accuracy. The study also highlights that open access to data significantly impacts the development of artificial intelligence technologies in healthcare.

Cybernetics and Physics(Volume 14, 2025 Number 2)
Kuban State Technological University (RU), Saint-Petersburg State University of Telecommunications (RU), Maikop State Technological University (RU)
Openalex Percentile: Top 60%
Retinal Imaging and Analysis
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