A Case of Thyroid-like Low Grade Nasopharyngeal Papillary Adenocarcinoma

Thyroid-like low grade nasopharyngeal papillary adenocarcinoma (TL-LGNPPA) is an extremely rare adenocarcinoma that arises in the posterior nasal septum or the nasopharynx, with histological findings similar to those of papillary thyroid carcinoma; the tumor shows positive immunohistochemistry for thyroid transcription factor-1 (TTF-1) but negative results for thyroglobulin. We performed endoscopic removal of a nasal tumor under general anesthesia in a pregnant woman, and the histopathological diagnosis was TL-LGNPPA.

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Publication Details

Journal
Practica Oto-Rhino-Laryngologica
Published
2025-01-01
DOI
https://doi.org/10.5631/jibirin.118.723
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

A Case of Thyroid-like Low Grade Nasopharyngeal Papillary Adenocarcinoma

Rui Sano, Masahiro Tsuge, Aya Motegi
Practica Oto-Rhino-Laryngologica
Salivary Gland Tumors Diagnosis and Treatment
article

A Case of Thyroid-like Low Grade Nasopharyngeal Papillary Adenocarcinoma

Rui Sano, Masahiro Tsuge, Aya Motegi
article en

Abstract

Thyroid-like low grade nasopharyngeal papillary adenocarcinoma (TL-LGNPPA) is an extremely rare adenocarcinoma that arises in the posterior nasal septum or the nasopharynx, with histological findings similar to those of papillary thyroid carcinoma; the tumor shows positive immunohistochemistry for thyroid transcription factor-1 (TTF-1) but negative results for thyroglobulin. We performed endoscopic removal of a nasal tumor under general anesthesia in a pregnant woman, and the histopathological diagnosis was TL-LGNPPA.

Practica Oto-Rhino-LaryngologicaVol. 118(10)
Chubu Rosai Hospital (JP)
Openalex Percentile: Top 57%
Salivary Gland Tumors Diagnosis and Treatment
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