Changes in the Phase Angle after Bariatric Surgery: A Meta-Analysis
Background: Phase angle (PhA), a parameter derived from bioelectrical impedance analysis, is associated with lean mass and muscle mass. Bariatric surgery can result in significant changes in body composition. The objective of this meta-analysis was to determine the impact of bariatric surgery on PhA. Methods: A systematic review and meta-analysis were conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, including studies up to January 2025 from five databases. Eligible studies assessed PhA alterations before and after bariatric surgery. Results: Thirteen studies with a total of 825 patients were included. Significant PhA reduction was observed following bariatric surgery (weighted mean difference: −0.922; 95% confidence interval [CI]: −1.063, −0.781; p < 0.001). Random-effects meta-regression showed a significant association between ΔPhA and ΔBMI (slope: 0.072; 95% CI: 0.033, 0.112; p = 0.0003) and Δfat-free mass (slope: 0.080; 95% CI: 0.052, 0.107; p < 0.001), but no association with Δfat mass. PhA values decreased significantly with following bariatric surgery, but there were no differences between Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG). Conclusions: This meta-analysis offers evidence regarding the impact of bariatric surgery on bioimpedance parameters, including PhA, in individuals with obesity.
Authors
- Kishore M. Gadde (ORCID: https://orcid.org/0000-0002-1856-5574)
- Amirhossein Sahebkar (ORCID: https://orcid.org/0000-0002-8656-1444)
- Elaheh Mirhadi (ORCID: https://orcid.org/0009-0003-9604-9449)
- Tannaz Jamialahmadi (ORCID: https://orcid.org/0000-0001-9521-3153)
- Wael Almahmeed (ORCID: https://orcid.org/0000-0003-0312-9910)
- Aida Tasbandi (ORCID: https://orcid.org/0000-0002-6741-1280)
- Sepideh Salehabadi
Institutions
- Mashhad University of Medical Sciences (IR)
- Biotechnology Research Center (IR)
- University of California, Irvine Medical Center (US)
- Chitkara University (IN)
Publication Details
- Journal
- Bariatric Surgical Practice and Patient Care
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1177/2168023x251384210
- Primary Topic
- Bariatric Surgery and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00