Interaction between toll-like receptor 4 polymorphism and abdominal obesity on ovarian cancer risk in Chinese women

The findings suggested that TLR4 gene rs4986790 and rs11536889 polymorphisms were associated with increased OC risk. Significant interaction also existed between rs4986790 and AO, which means that the WC levels may influence the impact of rs4986790 on OC risk.

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Publication Details

Journal
BMC Women s Health
Published
2025-09-29
DOI
https://doi.org/10.1186/s12905-025-04001-w
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Interaction between toll-like receptor 4 polymorphism and abdominal obesity on ovarian cancer risk in Chinese women

Feng Ni, Cheng Tan, Baixia Yang, Jiamin Zhu et al.
BMC Women s Health
Ovarian cancer diagnosis and treatment
article

Interaction between toll-like receptor 4 polymorphism and abdominal obesity on ovarian cancer risk in Chinese women

Feng Ni, Cheng Tan, Baixia Yang, Jiamin Zhu, Dan Tao, Xiaogang Zhai
article en

Abstract

The findings suggested that TLR4 gene rs4986790 and rs11536889 polymorphisms were associated with increased OC risk. Significant interaction also existed between rs4986790 and AO, which means that the WC levels may influence the impact of rs4986790 on OC risk.

BMC Women s HealthVol. 25(1)
Jiangyin People's Hospital (CN), Nantong Tumor Hospital (CN)
Openalex Percentile: Top 65%
Ovarian cancer diagnosis and treatment
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