Anesthetic Considerations in Pediatric Corneal Neurotization: A Case Report
Congenital corneal anesthesia (CCA) is a rare pediatric disorder characterized by absent or markedly reduced corneal sensation, predisposing to neurotrophic keratopathy and vision-threatening complications. Corneal neurotization has emerged as a surgical option to restore corneal innervation, but anesthetic considerations in pediatric cases remain scarcely reported. We present the anesthetic management of a six-year-old female child with CCA and recurrent herpetic keratitis following deep anterior lamellar keratoplasty, who underwent indirect corneal neurotization with a sural nerve graft. Anesthetic care focused on preoperative anxiety reduction, airway safety, multimodal analgesia, and limited neuromuscular blockade to facilitate intraoperative neuromonitoring. Standard monitoring included electrocardiography, non-invasive blood pressure, pulse oximetry, capnography, temperature, and ulnar nerve twitch assessment. Perioperative antiviral prophylaxis (oral acyclovir) was maintained, and ondansetron was administered for PONV prophylaxis. The four-hour procedure was uneventful, with stable hemodynamics and adequate postoperative pain control. Pain was assessed using the FLACC (Face, Legs, Activity, Cry, Consolability) scale, which remained at a level of <3/10 throughout the first 24 hours. This report highlights the importance of tailored anesthetic strategies in pediatric neurotization procedures, balancing surgical requirements with age-specific physiological considerations.
Authors
- Arturo Ramírez-Miranda (ORCID: https://orcid.org/0000-0001-6419-5116)
- John Vazquez
- Nicolás Kahuam-López (ORCID: https://orcid.org/0000-0003-3887-0629)
- Tania Albavera-Giles
- César Cárdenas (ORCID: https://orcid.org/0000-0003-1115-2790)
- Alfredo Aguilera (ORCID: https://orcid.org/0000-0001-8530-9397)
- Guillermo Raul Vera-Duarte
- Marcella G. A. Tirado
- Mauricio Muleiro-Alvarez
- Alejandra Botero-Benítez
- Neyra Xiomara Pérez Garcés
Institutions
- Plastic Surgery Hospital (CN)
- Ocular Proteomics (United States) (US)
Publication Details
- Journal
- Cureus
- Published
- 2025-09-30
- DOI
- https://doi.org/10.7759/cureus.93566
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00