Are Children Least Engaged with Health Care More Likely to Have Trachoma?

Distribution of azithromycin to children ages 0-9 years old is an established strategy for treating and preventing trachoma. Our study aimed to determine whether the order in which children show up for trachoma screening is correlated with their infection status. We used baseline visit data from the study Kebele Elimination of Trachoma for Ocular Health in Ethiopia. All children ages 0-9 years old in 20 randomly selected villages were tested for ocular Chlamydia trachomatis with polymerase chain reaction. We used mixed effects logistic regression to estimate the odds ratio (OR) of trachoma positivity on presentation day 1 versus later, with village as a random effect. There was no statistical difference between infection prevalence among children measured on day 1 versus those measured during the following days (OR = 0.89-fold, 95% CI: 0.65- to 1.21-fold, P = 0.44), indicating that presentation order is not a considerable factor in highly prevalent regions.

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Publication Details

Journal
American Journal of Tropical Medicine and Hygiene
Published
2025-09-30
DOI
https://doi.org/10.4269/ajtmh.24-0582
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
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article

Are Children Least Engaged with Health Care More Likely to Have Trachoma?

Hadley Burroughs, Catherine E. Oldenburg, Benjamin F. Arnold, Scott D. Nash et al.
American Journal of Tropical Medicine and Hygiene
Reproductive tract infections research
article

Are Children Least Engaged with Health Care More Likely to Have Trachoma?

Hadley Burroughs, Catherine E. Oldenburg, Benjamin F. Arnold, Scott D. Nash, Ariktha Srivathsan, Awraris Hailu Bilchut, Yeshigeta Gelaw, Seth Blumberg, Michael Deiner, Jessica G. Shantha, Esmael Habtamu, Ambahun Chernet, Huiyu Hu, Belay Beyene, Aemero Abateneh Mengesha, Ian Fetterman, Travis C. Porco, Thomas M. Lietman, Emmanuel Agu, Renee F. N. Casentini, Milan Hilde-Jones
article en

Abstract

Distribution of azithromycin to children ages 0-9 years old is an established strategy for treating and preventing trachoma. Our study aimed to determine whether the order in which children show up for trachoma screening is correlated with their infection status. We used baseline visit data from the study Kebele Elimination of Trachoma for Ocular Health in Ethiopia. All children ages 0-9 years old in 20 randomly selected villages were tested for ocular Chlamydia trachomatis with polymerase chain reaction. We used mixed effects logistic regression to estimate the odds ratio (OR) of trachoma positivity on presentation day 1 versus later, with village as a random effect. There was no statistical difference between infection prevalence among children measured on day 1 versus those measured during the following days (OR = 0.89-fold, 95% CI: 0.65- to 1.21-fold, P = 0.44), indicating that presentation order is not a considerable factor in highly prevalent regions.

American Journal of Tropical Medicine and HygieneVol. 113(6)
Debre Berhan University (ET), Carter Center (US), University of California, San Francisco (US), San Francisco Foundation (US), Amhara Regional Health Bureau (ET), Amhara Agricultural Research Institute (ET), The Carter Center (ET), Addis Ababa University (ET), Bahir Dar University (ET)
Openalex Percentile: Top 75%
Reproductive tract infections research
DOISourceOpenAlex
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