Murine hindlimb lymphedema model: optimization and evaluation of radiation

Radiation of the murine hindlimb model results in sustained lymphedema compared to non-irradiated mice. The murine hindlimb lymphedema model is clinically more translatable than the murine tail model with consistent results.

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Publication Details

Journal
Breast Cancer Research
Published
2025-09-29
DOI
https://doi.org/10.1186/s13058-025-02112-8
Citations
2
Primary Topic
Lymphatic System and Diseases
Type
article
Field-Weighted Citation Impact
2.09

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article

Murine hindlimb lymphedema model: optimization and evaluation of radiation

Shahnur Ahmed, Aladdin H. Hassanein, Ganesh Mohan, Helen Chin Sinex et al.
2 citations
Breast Cancer Research
Lymphatic System and Diseases
2.09
article

Murine hindlimb lymphedema model: optimization and evaluation of radiation

Shahnur Ahmed, Aladdin H. Hassanein, Ganesh Mohan, Helen Chin Sinex, Mithun Sinha, Désirée König, Marc S. Mendonca, Miguel D. Jorge, Angad S. Sidhu, Steven J. Sullivan, Christopher A. Subi-Kasozi
article en
2 citations

Abstract

Radiation of the murine hindlimb model results in sustained lymphedema compared to non-irradiated mice. The murine hindlimb lymphedema model is clinically more translatable than the murine tail model with consistent results.

Breast Cancer ResearchVol. 27(1)
Indiana Cancer Consortium (US), Indiana University – Purdue University Indianapolis (US)
Indiana University Health, National Institutes of Health
Openalex Percentile: Top 10%
Lymphatic System and Diseases
2.09
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