Advanced MRI based Alzheimer’s diagnosis through ensemble learning techniques

Alzheimer's Disease is a condition that affects the brain and causes changes in behavior and memory loss while making it hard to carry out tasks properly. It's vital to spot the illness early, for effective treatment. MRI technology has advanced in detecting Alzheimer's by using machine learning and deep learning models. These models use neural networks to analyze brain MRI results automatically and identify key indicators of Alzheimer's disease. In this study, we used MRI data to train a CNN for diagnosing and categorizing the four stages of Alzheimer's disease with deep learning techniques, offering significant advantages in identifying patterns in medical imaging for this neurodegenerative condition compared to using a CNN exclusively trained for this purpose. They evaluated ResNet50, InceptionResNetv2 as well as a CNN specifically trained for their study and found that combining the models led to highly accurate results. The accuracy rates for the trained CNN model stood at 90.76%, InceptionResNetv2 at 86.84%, and ResNet50 at 90.27%. In this trial run of the experiment conducted by combining all three models collaboratively resulted in an accuracy rate of 94.27% compared to the accuracy rates of each model working individually.

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Publication Details

Journal
Scientific Reports
Published
2025-09-30
DOI
https://doi.org/10.1038/s41598-025-04899-0
Primary Topic
Brain Tumor Detection and Classification
Type
article
Field-Weighted Citation Impact
0.00

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article

Advanced MRI based Alzheimer’s diagnosis through ensemble learning techniques

M. Thangavel, V Nivethitha, Suthir Sriram, T. P. Arun Kaarthic et al.
Scientific Reports
Brain Tumor Detection and Classification
article

Advanced MRI based Alzheimer’s diagnosis through ensemble learning techniques

M. Thangavel, V Nivethitha, Suthir Sriram, T. P. Arun Kaarthic, S. Archita
article en

Abstract

Alzheimer's Disease is a condition that affects the brain and causes changes in behavior and memory loss while making it hard to carry out tasks properly. It's vital to spot the illness early, for effective treatment. MRI technology has advanced in detecting Alzheimer's by using machine learning and deep learning models. These models use neural networks to analyze brain MRI results automatically and identify key indicators of Alzheimer's disease. In this study, we used MRI data to train a CNN for diagnosing and categorizing the four stages of Alzheimer's disease with deep learning techniques, offering significant advantages in identifying patterns in medical imaging for this neurodegenerative condition compared to using a CNN exclusively trained for this purpose. They evaluated ResNet50, InceptionResNetv2 as well as a CNN specifically trained for their study and found that combining the models led to highly accurate results. The accuracy rates for the trained CNN model stood at 90.76%, InceptionResNetv2 at 86.84%, and ResNet50 at 90.27%. In this trial run of the experiment conducted by combining all three models collaboratively resulted in an accuracy rate of 94.27% compared to the accuracy rates of each model working individually.

Scientific ReportsVol. 15(1)
Al Ain University (AE), United Arab Emirates University (AE), Amrita Vishwa Vidyapeetham (IN)
Amrita Vishwa Vidyapeetham University, United Arab Emirates University
Openalex Percentile: Top 66%
Brain Tumor Detection and Classification
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