Procedural learning worsens with OSA severity in older adults and is insensitive to short exposure supplemental oxygen therapy

As in younger adults, more severe sleep apnea is associated with worse motor procedural learning in older adults. However, a single night of NOS treatment had no effect on procedural learning, suggesting that OSA-related cognitive deficits result from chronic impacts of sleep disruption and hypoxia.

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Publication Details

Journal
Sleep Medicine
Published
2025-09-24
DOI
https://doi.org/10.1016/j.sleep.2025.106821
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Procedural learning worsens with OSA severity in older adults and is insensitive to short exposure supplemental oxygen therapy

Christian D. Harding, Sonia Jain, Atul Malhotra, Ina Djonlagic et al.
Sleep Medicine
Obstructive Sleep Apnea Research
article

Procedural learning worsens with OSA severity in older adults and is insensitive to short exposure supplemental oxygen therapy

Christian D. Harding, Sonia Jain, Atul Malhotra, Ina Djonlagic, Crystal Kwan, Pamela DeYoung, Breanna Holloway, Sonia Ancoli-Israel, Xiaoying Sun, Sarah J. Banks
article en

Abstract

As in younger adults, more severe sleep apnea is associated with worse motor procedural learning in older adults. However, a single night of NOS treatment had no effect on procedural learning, suggesting that OSA-related cognitive deficits result from chronic impacts of sleep disruption and hypoxia.

Sleep MedicineVol. 136
Beth Israel Deaconess Medical Center (US), UC San Diego Health System (US), Beth Israel Deaconess Hospital (US), University of California System (US), University of California San Diego (US), Human Longevity (United States) (US)
Openalex Percentile: Top 66%
Obstructive Sleep Apnea Research
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Procedural learning worsens with OSA severity in older adults and is insensitive to short exposure supplemental oxygen therapy — Christian D. Harding, Sonia Jain, et al. · Sleep Medicine (2025) | TGRS Research Map | TGRS