The Association of VDR <i>FokI</i> T&gt;C (rs2228570) Gene Variants With T2DM, and Its Complications: Influence on BMI, Oxidative Stress, and Dyslipidemia

This study indicates that the FokI CC genotype and the FokI C allele are associated with an increased risk of T2DM and its complications. We observed the influence of VDR FokI variants on dyslipidemia, oxidative stress, and BMI. It seems the risk factors of developing T2DM, obesity, and oxidative stress among women are more prevalent than in men.

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Publication Details

Journal
Journal of Clinical Laboratory Analysis
Published
2025-09-29
DOI
https://doi.org/10.1002/jcla.70090
Primary Topic
Vitamin D Research Studies
Type
article
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article

The Association of VDR FokI T>C (rs2228570) Gene Variants With T2DM, and Its Complications: Influence on BMI, Oxidative Stress, and Dyslipidemia

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Journal of Clinical Laboratory Analysis
Vitamin D Research Studies
article

The Association of VDR FokI T>C (rs2228570) Gene Variants With T2DM, and Its Complications: Influence on BMI, Oxidative Stress, and Dyslipidemia

Zahra Ghorbani, Armin Sharifi, Zohreh Rahimi, Ebrahim Shakiba, Mahsa Nouri
article en

Abstract

This study indicates that the FokI CC genotype and the FokI C allele are associated with an increased risk of T2DM and its complications. We observed the influence of VDR FokI variants on dyslipidemia, oxidative stress, and BMI. It seems the risk factors of developing T2DM, obesity, and oxidative stress among women are more prevalent than in men.

Journal of Clinical Laboratory AnalysisVol. 39(19)
Kermanshah University of Medical Sciences (IR)
Openalex Percentile: Top 62%
Vitamin D Research Studies
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