Endocarditis caused by Scopulariopsis brevicaulis with disseminated emboli and multiple vascular aneurysms: A case report and literature review

<i>S. brevicaulis</i> presents a significant treatment challenge due to its rare and opportunistic nature, along with frequent multi-drug resistance. Although there is no single optimal therapy for this mold, a practical approach combines medical and surgical strategies customized to individual cases, employing a variety of agents based on in vitro sensitivity testing. Determining minimum inhibitory concentrations (MICs) is essential for guiding treatment decisions, even in the absence of established clinical breakpoints for this pathogen. Olorofilm, a novel oral antifungal, demonstrates remarkable potential for treating <i>S. brevicaulis.</i>