A case of antisynthetase syndrome with interstitial lung disease in pregnancy

Antisynthetase syndrome (anti-SS) is an autoimmune condition characterised by autoantibodies against aminoacyl tRNA synthetases. Clinical features can include interstitial lung disease (ILD), myositis, Raynaud's phenomenon and arthritis. Described here is a 25-year-old pregnant woman with anti-SS with worsening ILD in the latter part of pregnancy, requiring emergency delivery at 36 weeks and 3 days of gestation.

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Publication Details

Journal
Obstetric Medicine
Published
2025-09-25
DOI
https://doi.org/10.1177/1753495x251380063
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
0.00
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article

A case of antisynthetase syndrome with interstitial lung disease in pregnancy

Charlotte Frise, Esther H.G. Park, Melissa Wickremasinghe, Kerry Munro
Obstetric Medicine
Inflammatory Myopathies and Dermatomyositis
article

A case of antisynthetase syndrome with interstitial lung disease in pregnancy

Charlotte Frise, Esther H.G. Park, Melissa Wickremasinghe, Kerry Munro
article en

Abstract

Antisynthetase syndrome (anti-SS) is an autoimmune condition characterised by autoantibodies against aminoacyl tRNA synthetases. Clinical features can include interstitial lung disease (ILD), myositis, Raynaud's phenomenon and arthritis. Described here is a 25-year-old pregnant woman with anti-SS with worsening ILD in the latter part of pregnancy, requiring emergency delivery at 36 weeks and 3 days of gestation.

Obstetric Medicine
Imperial College Healthcare NHS Trust (GB), Queen Charlotte's and Chelsea Hospital (GB)
Openalex Percentile: Top 64%
Inflammatory Myopathies and Dermatomyositis
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