Rescue of rocuronium-induced refractory anaphylax is with sugammadex in a laparoscopic hysterecto my: A case report

Neuromuscular blocking agents, particularly rocuronium, are a major cause of perioperative anaphylaxis. This report presents a rare and severe case of rocuronium-induced anaphylaxis in a 50-year-old woman undergoing an elective total laparoscopic hysterectomy at a tertiary care center in Eastern Nepal. Despite multiple doses of intravenous epinephrine, the patient did not achieve adequate hemodynamic recovery. However, a single bolus of sugammadex resulted in the rapid and complete resolution of symptoms. This case highlights the potential of sugammadex as a life-saving adjunct in treating NMBA-induced anaphylaxis that is unresponsive to standard inter ventions.

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Publication Details

Journal
Perioperative Precision Medicine
Published
2025-09-25
DOI
https://doi.org/10.61189/655401cvkjpp
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
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article

Rescue of rocuronium-induced refractory anaphylax is with sugammadex in a laparoscopic hysterecto my: A case report

Kanak Khanal, Prakash Bista, Lalit Kumar Rajbanshi, Rahul Kumar Chaudhary
Perioperative Precision Medicine
Anesthesia and Sedative Agents
article

Rescue of rocuronium-induced refractory anaphylax is with sugammadex in a laparoscopic hysterecto my: A case report

Kanak Khanal, Prakash Bista, Lalit Kumar Rajbanshi, Rahul Kumar Chaudhary
article en

Abstract

Neuromuscular blocking agents, particularly rocuronium, are a major cause of perioperative anaphylaxis. This report presents a rare and severe case of rocuronium-induced anaphylaxis in a 50-year-old woman undergoing an elective total laparoscopic hysterectomy at a tertiary care center in Eastern Nepal. Despite multiple doses of intravenous epinephrine, the patient did not achieve adequate hemodynamic recovery. However, a single bolus of sugammadex resulted in the rapid and complete resolution of symptoms. This case highlights the potential of sugammadex as a life-saving adjunct in treating NMBA-induced anaphylaxis that is unresponsive to standard inter ventions.

Perioperative Precision MedicineVol. 3(3)
Openalex Percentile: Top 57%
Anesthesia and Sedative Agents
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Rescue of rocuronium-induced refractory anaphylax is with sugammadex in a laparoscopic hysterecto my: A case report — Kanak Khanal, Prakash Bista, et al. · Perioperative Precision Medicine (2025) | TGRS Research Map | TGRS