Lithospermum erythrorhizon extract alleviates immunosuppression via MAPK signaling pathway
LEE effectively ameliorates dexamethasone-induced immunosuppression by restoring immune cell activity, regulating cytokine balance, and preserving immune organ structure, primarily via MAPK pathway regulation. This study provides a scientific basis for the development of LEE as a natural immunomodulatory agent in managing immunosuppression in mammals.
Authors
- Renhua Gai (ORCID: https://orcid.org/0000-0002-5866-0971)
- Qinjie Weng (ORCID: https://orcid.org/0000-0001-8026-0109)
- Xiaoqing Chi (ORCID: https://orcid.org/0000-0003-3336-7370)
- Ping Li (ORCID: https://orcid.org/0000-0001-7062-4327)
Institutions
- Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-09-29
- DOI
- https://doi.org/10.3389/fvets.2025.1654212
- Citations
- 1
- Primary Topic
- Bioactive Compounds and Antitumor Agents
- Type
- article
- Field-Weighted Citation Impact
- 1.31