School Performance After Maintenance Tocolysis With Nifedipine for Threatened Preterm Birth: 12‐Year Follow‐Up of the <scp>APOSTEL</scp> 2 Trial
Children prenatally exposed to maintenance tocolysis with nifedipine had significantly poorer school performance at 12 years of age compared to those exposed to placebo. These findings further discourage nifedipine's use for maintenance tocolysis, and more research is warranted regarding its long-term effects on child development.
Authors
- Marc E. A. Spaanderman (ORCID: https://orcid.org/0000-0002-7837-5019)
- Larissa I. van der Windt (ORCID: https://orcid.org/0000-0001-8443-1702)
- Carolien Roos (ORCID: https://orcid.org/0000-0003-0994-9223)
- Anita C.J. Ravelli (ORCID: https://orcid.org/0000-0002-3447-8286)
- Martijn A. Oudijk (ORCID: https://orcid.org/0000-0001-8672-4365)
- Ben W. Mol (ORCID: https://orcid.org/0000-0001-8337-550X)
- Eva Pajkrt (ORCID: https://orcid.org/0000-0002-4432-3691)
- Hubertina Scheepers (ORCID: https://orcid.org/0000-0001-9215-5795)
- Jim A. L. Meliezer
Institutions
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- Amsterdam University Medical Centers (NL)
- Maastro Clinic (NL)
- Monash University (AU)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- BJOG An International Journal of Obstetrics & Gynaecology
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1111/1471-0528.70030
- Primary Topic
- Infant Development and Preterm Care
- Type
- article
- Field-Weighted Citation Impact
- 0.00