Comparative Long-Term Effectiveness of Nintedanib and Pirfenidone in Idiopathic Pulmonary Fibrosis: A Systematic Literature Review

Introduction: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease. Pirfenidone and nintedanib slow progression, but no head-to-head randomized trials have tested their long-term effectiveness, particularly in real-world and advanced disease.