Effects of dietary L-glutamate and L-aspartate supplementation on growth performance, severity of diarrhea, intestinal barrier integrity, and fecal microbiota of weaned piglets challenged with F18 enterotoxigenic Escherichia coli
Supplementation with L-glutamate or L-aspartate promoted growth performance, supported gut health, and enhanced disease resistance in weaned pigs challenged with F18 ETEC. During the weaning period, L-glutamate or L-aspartate could potentially be considered conditionally essential amino acids, helping to alleviate weaning complications and reduce the need for antibiotic use in swine farming.
Authors
- Kunal Dixit (ORCID: https://orcid.org/0000-0002-1334-6997)
- Xunde Li (ORCID: https://orcid.org/0000-0002-0908-4234)
- S Mohan (ORCID: https://orcid.org/0000-0001-9118-4236)
- Kwangwook Kim (ORCID: https://orcid.org/0000-0001-5854-6047)
- Supatirada Wongchanla
- Xiaojing Li (ORCID: https://orcid.org/0000-0003-1660-3108)
- Yanhong Liu (ORCID: https://orcid.org/0000-0001-7727-4796)
- Sangwoo Park (ORCID: https://orcid.org/0000-0003-2288-1374)
- Maria L. Marco (ORCID: https://orcid.org/0000-0002-3643-9766)
- S. Palomares
- Shuhan Sun
- Alejandra Mejía-Caballero (ORCID: https://orcid.org/0000-0003-0240-2997)
Institutions
- United Animal Health (United States) (US)
- University of California, Davis (US)
- Michigan State University (US)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1186/s40104-025-01266-x
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Novo Nordisk