Metasurface-assisted adaptive quantum phase contrast imaging

Phase contrast microscopy is essential in optical imaging, but traditional systems are bulky and limited by single-phase modulation, hindering visualization of complex specimens.Metasurfaces, with their subwavelength structures, offer compact integration and versatile light field control.Quantum imaging further enhances performance by leveraging nonclassical photon correlations to suppress classical noise, improve contrast, and enable multifunctional processing.Here, we report, a dual-mode bright-dark phase contrast imaging scheme enabled by quantum metasurface synergy.By combining polarization entanglement from quantum light sources with metasurface phase modulation, our method achieves highcontrast, adaptive bright-dark phase contrast imaging of transparent samples with arbitrary phase distributions under low-light conditions.Compared to classical weak light imaging, quantum illumination suppresses environmental noise at equivalent photon flux, improving the contrast from 0.22 to 0.81.Moreover, quantum polarization entanglement enables remote switching to ensure high-contrast imaging in at least one mode, supporting dynamic observation of biological cells with complex phase structures.This capability is especially valuable in scenarios where physical intervention is difficult, such as in miniaturized systems, in vivo platforms, or extreme environments.Overall, the proposed scheme offers an efficient noninvasive solution for biomedical imaging with strong potential in life science applications.