Unravelling genomic differences in cerebrospinal fluid: patients with lung cancer with combined brain parenchymal and meningeal metastasis versus exclusive meningeal metastasis
This study revealed significant differences in CSF genomic characteristics between patients with simultaneous BM and MM of lung cancer and patients with MM only. These differences provide potential biomarkers for the precise treatment of patients with brain metastases and help to distinguish patients with lung cancer brain metastases with different metastatic patterns.
Authors
- Yuan Lv (ORCID: https://orcid.org/0000-0001-5889-2695)
- Jinduo Li
- Xiaomin Liu (ORCID: https://orcid.org/0000-0003-2155-3627)
- Lin Li (ORCID: https://orcid.org/0000-0001-8349-9588)
- Liwei Sun (ORCID: https://orcid.org/0000-0003-2926-8839)
Institutions
- Tianjin University of Technology (CN)
- Tianjin University (CN)
- Tianjin Huanhu Hospital (CN)
- Tianjin Institute of Pharmaceutical Research (China) (CN)
- Beijing Institute of Neurosurgery (CN)
Publication Details
- Journal
- Journal of Neuro-Oncology
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1007/s11060-025-05224-5
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00