Approach to Thrombocytopenia in Critical Care

Thrombocytopenia is one of the most frequently encountered haematological abnormalities in critically ill patients, with reported incidence ranging from 13–65% [1]. It is defined as a platelet count <150,000/µL or a decline of >50% from baseline. The condition may develop due to multiple, often overlapping mechanisms, and its presence in ICU patients correlates with increased morbidity, mortality, and prolonged ICU stay.