Oral administration of low‐molecular‐weight heparin ameliorates colitis by enhancing the gut mucus barrier via microbial tryptophan metabolites
The results provide new insights into the signalling mechanisms associated with the therapeutic potential of LMWH in colitis, and highlight the application of IPA for UC treatment.
Authors
- Dekai Zheng (ORCID: https://orcid.org/0000-0001-5783-3300)
- Liping Liang
- Xiuying Liu (ORCID: https://orcid.org/0000-0001-6414-6349)
- Weihao Tan (ORCID: https://orcid.org/0009-0000-4765-865X)
- Cangui Zhang
- Le Liu (ORCID: https://orcid.org/0000-0002-9270-9951)
- Shaoheng Zhang (ORCID: https://orcid.org/0000-0002-4768-0088)
- Ying Wang (ORCID: https://orcid.org/0000-0002-3671-4836)
- Jian Sun
- Ye Chen (ORCID: https://orcid.org/0000-0002-7964-7899)
- Qing Qing (ORCID: https://orcid.org/0000-0003-4715-0113)
- Shuze Chen
- Zhi Wang (ORCID: https://orcid.org/0000-0002-6832-7013)
- Hanxiao Feng (ORCID: https://orcid.org/0000-0001-9474-4892)
Institutions
- Third Affiliated Hospital of Guangzhou Medical University (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2025-09-28
- DOI
- https://doi.org/10.1111/bph.70209
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00