Successful treatment of solar lentigines using a novel 532-nm nanosecond neodymium-doped yttrium aluminum garnet vasculature salvage laser surgery system: case series

Solar lentigines are benign pigmented lesions commonly treated with 532-nm Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers, though outcomes can be limited by post-inflammatory hyperpigmentation (PIH), especially in darker skin types.This case series evaluated a novel 532-nm nanosecond Nd:YAG vasculature salvage laser surgery (VSLS) system, designed to minimize PIH risk through two key features: cryo-photothermolysis, which induces vasoconstriction to reduce hemoglobin absorption, and AutoDerm, which enables precise lesion targeting.Two female patients in their 60s with persistent solar lentigines, unresponsive to prior laser treatments, underwent a single VSLS session.Complete resolution of the lentigines was achieved after one treatment session, with no signs of PIH, prolonged erythema, or scarring observed throughout 3 months of follow-up.This outcome suggests the VSLS system may offer a safer and more effective alternative for treating solar lentigines, particularly in patients at a higher risk of laser-induced complications.

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Publication Details

Journal
Medical Lasers
Published
2025-08-28
DOI
https://doi.org/10.25289/ml.25.014
Primary Topic
Dermatologic Treatments and Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Successful treatment of solar lentigines using a novel 532-nm nanosecond neodymium-doped yttrium aluminum garnet vasculature salvage laser surgery system: case series

Sang Ju Lee, Jeanne Jung, Young In Lee, Ngoc Ha Nguyen
Medical Lasers
Dermatologic Treatments and Research
article

Successful treatment of solar lentigines using a novel 532-nm nanosecond neodymium-doped yttrium aluminum garnet vasculature salvage laser surgery system: case series

Sang Ju Lee, Jeanne Jung, Young In Lee, Ngoc Ha Nguyen
article en

Abstract

Solar lentigines are benign pigmented lesions commonly treated with 532-nm Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers, though outcomes can be limited by post-inflammatory hyperpigmentation (PIH), especially in darker skin types.This case series evaluated a novel 532-nm nanosecond Nd:YAG vasculature salvage laser surgery (VSLS) system, designed to minimize PIH risk through two key features: cryo-photothermolysis, which induces vasoconstriction to reduce hemoglobin absorption, and AutoDerm, which enables precise lesion targeting.Two female patients in their 60s with persistent solar lentigines, unresponsive to prior laser treatments, underwent a single VSLS session.Complete resolution of the lentigines was achieved after one treatment session, with no signs of PIH, prolonged erythema, or scarring observed throughout 3 months of follow-up.This outcome suggests the VSLS system may offer a safer and more effective alternative for treating solar lentigines, particularly in patients at a higher risk of laser-induced complications.

Medical LasersVol. 14(3)
Yonsei University (KR), University of Medicine and Pharmacy at Ho Chi Minh City (VN)
Korea International Cooperation Agency
Openalex Percentile: Top 53%
Dermatologic Treatments and Research
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