OPTIMIZATION TYPE OF STIFFENING AGENT IN FORMULATION CREAM Melastoma malabathricum L. LEAF WATER FRACTION

The skin is one of the visible outer parts of the body, and cosmetics are used for its care. Senggani (Melastoma malabathricum) leaves contain flavonoids, saponins, alkaloids, tannins, and polyphenols. The polyphenol content found in M. malabathricum leaves has high antioxidant activity and has the potential to be used as a sunscreen that can block the negative effects of UVA and UVB rays. These secondary metabolites can be obtained from the water fraction and used as antioxidants in cream preparations. Cream formulations require compounds that can maintain the consistency of the preparation to produce good physical properties and stability. This study aimed to analyze the type of stiffening agent in the formulation of cream preparation of aqueous fraction of senggani leaf (Melastoma malabathricum L.) using organoleptical tests, homogeneity, pH, spreadability, adhesiveness, and viscosity of cream preparation. The results showed that cetyl alcohol (FII) has different physical properties, and the evaluation and accelerated stability test (cycling test) resulted in the most physically stable preparation, as evidenced by the sig. (p value) > 0.05, indicating that storage did not affect the cream preparation. Keywords: senggani leaf (Melastoma malabathricum L.), water fraction, cream, cycling test

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Publication Details

Journal
Medical Sains Jurnal Ilmiah Kefarmasian
Published
2025-09-30
DOI
https://doi.org/10.37874/ms.v10i3.1607
Primary Topic
Irrigation Practices and Water Management
Type
article
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article

OPTIMIZATION TYPE OF STIFFENING AGENT IN FORMULATION CREAM Melastoma malabathricum L. LEAF WATER FRACTION

Desy Siska Anastasia, Pratiwi Apridamayanti, Raden Hasya Nadhira, Meri Ropiqa
Medical Sains Jurnal Ilmiah Kefarmasian
Irrigation Practices and Water Management
article

OPTIMIZATION TYPE OF STIFFENING AGENT IN FORMULATION CREAM Melastoma malabathricum L. LEAF WATER FRACTION

Desy Siska Anastasia, Pratiwi Apridamayanti, Raden Hasya Nadhira, Meri Ropiqa
article en

Abstract

The skin is one of the visible outer parts of the body, and cosmetics are used for its care. Senggani (Melastoma malabathricum) leaves contain flavonoids, saponins, alkaloids, tannins, and polyphenols. The polyphenol content found in M. malabathricum leaves has high antioxidant activity and has the potential to be used as a sunscreen that can block the negative effects of UVA and UVB rays. These secondary metabolites can be obtained from the water fraction and used as antioxidants in cream preparations. Cream formulations require compounds that can maintain the consistency of the preparation to produce good physical properties and stability. This study aimed to analyze the type of stiffening agent in the formulation of cream preparation of aqueous fraction of senggani leaf (Melastoma malabathricum L.) using organoleptical tests, homogeneity, pH, spreadability, adhesiveness, and viscosity of cream preparation. The results showed that cetyl alcohol (FII) has different physical properties, and the evaluation and accelerated stability test (cycling test) resulted in the most physically stable preparation, as evidenced by the sig. (p value) > 0.05, indicating that storage did not affect the cream preparation. Keywords: senggani leaf (Melastoma malabathricum L.), water fraction, cream, cycling test

Medical Sains Jurnal Ilmiah KefarmasianVol. 10(3)
Tanjungpura University (ID)
Openalex Percentile: Top 66%
Irrigation Practices and Water Management
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OPTIMIZATION TYPE OF STIFFENING AGENT IN FORMULATION CREAM Melastoma malabathricum L. LEAF WATER FRACTION — Desy Siska Anastasia, Pratiwi Apridamayanti, et al. · Medical Sains Jurnal Ilmiah Kefarmasian (2025) | TGRS Research Map | TGRS