Cyclosporin A Monitoring in Allogeneic Hematopoietic Stem-Cell Transplant Recipients: A Comparison Between Siemens Viva-ProE System and LC-MS/MS

The developed LC-MS/MS assay demonstrated acceptable performance in measuring CsA concentration in whole blood. The comparison between the 2 methods highlights the need for method specification in therapeutic drug monitoring and provides regression equations to enhance the monitoring accuracy in clinical practice.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2025-09-29
DOI
https://doi.org/10.1097/ftd.0000000000001390
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

Cyclosporin A Monitoring in Allogeneic Hematopoietic Stem-Cell Transplant Recipients: A Comparison Between Siemens Viva-ProE System and LC-MS/MS

Xuemei Wu, Hongqiang Qiu, Qinghui Fu, Yisheng Chen et al.
Therapeutic Drug Monitoring
Hematopoietic Stem Cell Transplantation
article

Cyclosporin A Monitoring in Allogeneic Hematopoietic Stem-Cell Transplant Recipients: A Comparison Between Siemens Viva-ProE System and LC-MS/MS

Xuemei Wu, Hongqiang Qiu, Qinghui Fu, Yisheng Chen, Xueyong Li, Yingbin Huang, Guan‐Hua Lai, Rongqi Lin, Kaixian Lai, Yu Cheng, Xiaozhen Fan, Ming Chen
article en

Abstract

The developed LC-MS/MS assay demonstrated acceptable performance in measuring CsA concentration in whole blood. The comparison between the 2 methods highlights the need for method specification in therapeutic drug monitoring and provides regression equations to enhance the monitoring accuracy in clinical practice.

Therapeutic Drug Monitoring
Fujian University of Traditional Chinese Medicine (CN), Fujian Medical University (CN), People’s Hospital of Wenshan Prefecture (CN), Union Hospital (CN)
Openalex Percentile: Top 65%
Hematopoietic Stem Cell Transplantation
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