BMP8A, TGF-β1 regulates chicken chondrocyte proliferation, differentiation, and apoptosis induced by Thiram
BMP8A plays a protective role in TD by the regulation of collagen balance and the maintenance of chondrocyte function, especially in the presence of high TGF-β1 levels. VD3 supplementation effectively reduces TD-related damage. The interaction between BMP8A and TGF-β1 may provide a novel therapeutic target for the prevention and treatment of TD in poultry.
Authors
- Xiaoling Zhao (ORCID: https://orcid.org/0000-0002-0633-4701)
- Felix Kwame Amevor (ORCID: https://orcid.org/0000-0003-2682-1993)
- Ranran Du
- Hengyong Xu (ORCID: https://orcid.org/0000-0001-8279-6820)
- Yuxin Zhou (ORCID: https://orcid.org/0009-0000-3285-9379)
- Yuan Lu (ORCID: https://orcid.org/0000-0003-2347-2521)
- Yiping Liu (ORCID: https://orcid.org/0000-0002-2554-3269)
- Zhi Hu
- Xiangtian Ji
- Yan Wang (ORCID: https://orcid.org/0000-0002-1743-6383)
Institutions
- Sichuan Agricultural University (CN)
- Ministry of Agriculture (ID)
Publication Details
- Journal
- Animal Bioscience
- Published
- 2025-09-30
- DOI
- https://doi.org/10.5713/ab.25.0413
- Citations
- 1
- Primary Topic
- Animal Nutrition and Physiology
- Type
- article
- Field-Weighted Citation Impact
- 1.19
Funders
- National Natural Science Foundation of China