PNNL-Predictive-Phenomics/ProteoMeter

ProteoMeter is a Python package that assists in the statistical analysis of global proteomics, protein post-translation modification (PTM), and limited proteolysis (LiP) data. It contains batch correction, normalization, and statistical testing methods, as well as functions that "roll up" peptide-level data to the single-site level. It has a robust user configuration system, allowing it to flexibly integrate different types of experiment designs. For basic usage, a simple configuration file provides the essential functionality. Advanced users have access to the entire statistical pipeline for fine-tuning analyses. Processed data is easily exported to many common spreadsheet and data-frame formats.

Authors

Institutions

Publication Details

Journal
OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
Published
2025-01-01
DOI
https://doi.org/10.11578/dc.20250514.2
Primary Topic
Advanced Proteomics Techniques and Applications
Type
article
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article

PNNL-Predictive-Phenomics/ProteoMeter

Jordan C. Rozum, Song Feng, Nellie Ciesielski
OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
Advanced Proteomics Techniques and Applications
article

PNNL-Predictive-Phenomics/ProteoMeter

Jordan C. Rozum, Song Feng, Nellie Ciesielski
article en

Abstract

ProteoMeter is a Python package that assists in the statistical analysis of global proteomics, protein post-translation modification (PTM), and limited proteolysis (LiP) data. It contains batch correction, normalization, and statistical testing methods, as well as functions that "roll up" peptide-level data to the single-site level. It has a robust user configuration system, allowing it to flexibly integrate different types of experiment designs. For basic usage, a simple configuration file provides the essential functionality. Advanced users have access to the entire statistical pipeline for fine-tuning analyses. Processed data is easily exported to many common spreadsheet and data-frame formats.

OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
Pacific Northwest National Laboratory (US)
Advanced Proteomics Techniques and Applications
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