Comparison of efficacy and side effects between short-course radiotherapy and chemotherapy with or without immunotherapy in the neoadjuvant treatment for patients with locally advanced rectal cancer
Compared to SCRT combined with ChT alone, the combination of SCRT with ChT and IT significantly improves CR rate after neoadjuvant treatment, and the treatment-related adverse effects were tolerable.
Authors
- Yunying Yang (ORCID: https://orcid.org/0000-0002-5176-038X)
- Shaoqing Niu (ORCID: https://orcid.org/0000-0003-1070-0601)
- Yong Bao (ORCID: https://orcid.org/0000-0001-9591-4224)
- Chuangqi Chen (ORCID: https://orcid.org/0000-0003-0361-1301)
- Yangchan Li (ORCID: https://orcid.org/0000-0002-0354-7621)
- Jie Wen (ORCID: https://orcid.org/0000-0002-7166-0204)
- Jianqi Xiong
- Zhuangzhuang Yang
- Jiayi Yang (ORCID: https://orcid.org/0000-0003-2372-5197)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-09-29
- DOI
- https://doi.org/10.3389/fonc.2025.1630570
- Primary Topic
- Colorectal and Anal Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province