Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis
Osteomyelitis was associated with significant alterations in peripheral immune cell counts, particularly lymphocyte counts, which showed a strong positive correlation with the disease risk. These findings pave the way for future immunotherapeutic approaches for the treatment of osteomyelitis.
Authors
- Yong Zhi (ORCID: https://orcid.org/0000-0002-6970-3076)
- Gang Jin (ORCID: https://orcid.org/0000-0001-6713-1185)
- Yan Li (ORCID: https://orcid.org/0000-0003-1963-839X)
- Dong Wang (ORCID: https://orcid.org/0000-0002-6107-7023)
- Juan Li (ORCID: https://orcid.org/0000-0002-7489-4778)
- Yong-Hong Zhang (ORCID: https://orcid.org/0000-0002-3317-5734)
- Zemin Liu (ORCID: https://orcid.org/0000-0002-2261-2812)
- Shengxian Ge
Institutions
- Shanxi Medical University (CN)
- Second Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-09-29
- DOI
- https://doi.org/10.3389/fmed.2025.1669180
- Citations
- 1
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Natural Science Foundation of China