DMPS-induced neurological deterioration in neurological Wilson’s disease patients: a retrospective case-control study on clinical characteristics and risk factors
Neurological deterioration in DMPS-induced neurological WD patients is not rare and predominantly occurs in males. We identified three independent risk factors for this deterioration: sex, brain MRI score, and HCY. A composite risk model incorporating these parameters achieved superior predictive accuracy compared to individual biomarker.
Authors
- Shuang Jia (ORCID: https://orcid.org/0000-0001-8705-6055)
- Lulu Tang (ORCID: https://orcid.org/0000-0003-0612-9780)
- Guran Yu (ORCID: https://orcid.org/0000-0002-9356-8695)
- Yannan Gao
- Jing Zhang (ORCID: https://orcid.org/0009-0004-0512-3816)
- Wenming Yang (ORCID: https://orcid.org/0000-0003-1047-5328)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Anhui University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-09-29
- DOI
- https://doi.org/10.3389/fneur.2025.1599209
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Anhui University